Alex co-founded Intrinsic Medicine and has served as our Chief Executive Officer and board member since August 2018 and as the Chairman of our Board of Directors since March 2021. From February 2018 until December 2018, he provided commercialization and corporate development consulting services to several drug development companies. Alex served as Director, Corporate Development of Ionis Pharmaceuticals, a biotechnology company headquartered in Carlsbad, California, specializing in developing RNA-targeted therapeutics, and in similar roles of increasing responsibilities where his contributions guided strategic planning, corporate development and research and development decision making over the seven years leading to February 2018. Previously, he co-founded and served as Director of Business Development and Legal Affairs and as a board member of a clinical-stage digital health company, and was an associate attorney with Wilson Sonsini Goodrich & Rosati, a U.S. law firm headquartered in Palo Alto specializing in business, securities and corporate law. He received his Juris Doctor from the University of Michigan Law School and his Bachelor of Arts in Health & Societies from the University of Pennsylvania, College of Arts & Sciences.

Jason co-founded Intrinsic Medicine and has served as our President and board member since August 2018. From April 2018 until March 2020, he also provided intellectual property consulting services to early-stage drug development companies. Jason served in diverse management roles with Ionis Pharmaceuticals, including as Vice President, Regulatory Affairs and Corporate Development of Ionis Pharmaceuticals from May 2016 until April 2018, Vice President, Patents and Corporate Development from March 2012 to May 2016 and Vice President, Patents and Senior Patent Counsel from January 2009 until March 2012, as well as in various positions within the patent department from June 2004 until January 2009, including leading the department beginning in 2007. Before joining Ionis, he served as patent counsel for Enanta Pharmaceuticals, Inc. and patent manager for the Dana-Farber Cancer Institute. Prior to becoming an attorney, Jason was a research medicinal chemist. He received his Juris Doctor from Suffolk University Law School, cum laude, with an Intellectual Property Concentration with Distinction, his Master of Arts in Chemistry from San Diego State University, and his Bachelor of Science in Biochemistry with an emphasis in Chemistry from the University of California, Riverside.

Dr. Chuang has served as our Chief Medical Officer since September 2021. Dr. Chuang has worked as a consultant for Chuang Global Consulting, providing consulting services to companies in the life science industry since August 2016. Prior to joining Intrinsic Medicine, Dr. Chuang served as Vice President, Precision Medicine for Progenity, Inc., a biotechnology company developing molecular testing products and novel therapeutics, from July 2018 until December 2020, where he led the Clinical Translational and Clinical Operations departments, and was also an Officer of the company. Prior to that he served as Global Head of Translational Research and Early Clinical, Gastroenterology for Takeda Pharmaceuticals, a global biopharmaceutical company, from October 2016 until June 2018, where he was responsible for advancing early clinical assets to proof-of-concept stage of development. Dr. Chuang has served in numerous other leadership roles, including as Head of GI Clinical Development and Medical Affairs at Prometheus, where he worked on diagnostic and therapeutic products for patients with IBS and IBD. He joined Nestle Health Science in Switzerland following its acquisition of Prometheus in 2012, where for almost four years he helped develop Nestle’s strategy to bridge medical foods with therapeutics to deliver safer and efficacious products and was responsible for filing the first IND ever for a medical food. Dr. Chuang completed his GI and Nutrition training at Children’s Hospital of Philadelphia. He then joined the faculty at Duke University and the University of Pennsylvania before transitioning to the pharmaceuticals industry. He has authored over 70 peer-reviewed publications, abstracts and book chapters. Dr. Chuang received his medical degree at the University of Sydney and completed his pediatric specialty training in Australia before moving to the United States.

Dustin practiced as an attorney in the mergers & acquisitions practice of Davis, Polk and Wardwell, an international law firm headquartered in New York City, from July until September 2021 and in the corporate and transactional practice of Hall, Estill, Hardwick, Gable, Golden & Nelson, P.C. a regional law firm headquartered in Tulsa, Oklahoma, from February 2020 until July 2021. Prior to joining Hall Estill, Dustin served as Senior Counsel and Assistant Corporate Secretary of SandRidge Energy, Inc., an energy company headquartered in Oklahoma City, Oklahoma, from July 2014 to February 2020 and, previously, in similar roles of increasing responsibilities with Chesapeake Energy Corporation. Prior to joining Chesapeake, Mr. Crawford began his legal career as an attorney in the finance practice in the New York office of Bracewell LLP (formerly Bracewell & Giuliani LLP) an international law firm headquartered in Houston, Texas. He received his Juris Doctor from Columbia Law School, where he was President and Editor-in-Chief of the Columbia Journal of Environmental Law, and his Bachelor of Science in Biochemistry, magna cum laude, from the University of Nevada, Las Vegas.

Dave has served as the VP of Clinical Operations for Intrinsic Medicine since September 2021. Prior to that he served in consulting roles in the clinical development industry. He has over 30 years of experience in clinical development spanning pharmaceutical, biotech, and medical devices in the therapeutic areas of gastroenterology, oncology, autoimmune diseases, central nervous system (CNS) and veterinary indications. He has extensive experience in early phase from First in Human, SAD/MAD studies, Bioequivalence, TQT, as well as large global phase 3 programs in Asia, Central and Western Europe, as well as North America. He has led clinical operations teams with responsibilities for all outsourcing and vendor oversight, project and site management, clinical budgeting, clinical QA, and data management. Prior to joining Intrinsic Medicine, he was Sr Director, and Head of Clinical Operations at Progenity Inc., and worked several years as a senior global program consultant for large IBD programs for Nestle Health Sciences. Prior to that, he was Sr Director of Clinical Operations at Armagen, and Director of Clinical Operations at Arena Pharmaceuticals for five years leading the clinical operations team through FIM and phase 3 execution and FDA submission. Additionally, Dave has worked on multiple late stage programs for large CROs as well as Head of Clinical Operations for an oncology-focused specialty CRO. He received his Bachelor of Science in Animal Science/Physiology from the University of California, Davis

Michelle has served as our Director, Operations and Corporate Development since October 2021, prior to which she consulted for the Company as a business operations consultant from January 2021. She also provided independent consulting services for biotechnology startups and small businesses in fields including operations and program management, finance, procurement, and human resources, from October 2020 until October 2021. Prior to joining Intrinsic Medicine, Michelle served as Senior Manager, Business Operations for Sirenas LLC, an early-stage drug discovery company using computational metabolomics to uncover biological and chemical insights for small molecule therapeutics based in San Diego, California, from April 2015 until September 2020. Throughout her career as a senior business operations professional, she has approached her work with an entrepreneurial spirit, growing innovative startups at the speed of biotech. She earned her Master of Business Administration from the Rady School of Management at the University of California, San Diego, bridging the gap to Biotechnology after receiving her Bachelor of Science in Microbiology from the University of California, San Diego.

Alyssa has served as our Associate Director, Corporate Affairs and Patient Engagement since April 2022, prior to which she led commercial readiness efforts at Revance Therapeutics, a biotechnology company focused on innovative aesthetic and therapeutic indications. At Revance, Alyssa held a variety of roles with increasing responsibility across corporate affairs, product marketing and management in commercial aesthetics and therapeutics, and HCP digital marketing. Prior to joining Revance, Alyssa spent more than three years at Ionis Pharmaceuticals, the leader in discovering and developing RNA-targeted therapeutics, with increasing responsibilities supporting Corporate Communications, Public Relations and Investor Relations ensuring the corporate brand and reputation was consistently elevated across all platforms. Her time at Ionis allowed her to become familiar with the world of orphan diseases and find her passion in supporting those who suffer from rare and/or difficult to treat medical conditions. Throughout her accomplished career, Alyssa has led effectively through collaboration with scientists, commercial partners, advocacy groups, patients, and healthcare professionals. She earned her Master of Business and Science at Keck Graduate Institute and a Bachelor of Science in Biology at Chapman University.

Nichole has served as our Executive Assistant since November 2021. Nichole is a highly skilled Executive Assistant with nearly a decade of experience working alongside C-level executives. Before joining Intrinsic Medicine, Nichole served for 7 years as Executive Administrative Assistant for the Chief Operating Officer in Merchandising at Costco Wholesale in Issaquah, WA. Nichole provided direct support to the COO and multiple Senior Vice Presidents across several corporate departments, led teams of varying size and level, and managed multiple facets of administration. In addition to supporting daily operational functions, she directly managed Directors’ meetings, international teleconferences, and corporate events involving facilitation of internal and external communications, development of presentation materials, as well as preparation of executives for meetings, staffing, and training. Dedicated to creating operational impact and value, Nichole mentored new admins company-wide and continues to work creatively and collaboratively to ensure efficient progress towards business objectives.